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Medulloblastoma (MB) accounts for approximately 20% of pediatric central nervous system neoplasms. Current standard management includes safe maximal surgical resection followed by craniospinal irradiation (CSI) with chemotherapeutic radiosensitization followed by adjuvant chemotherapy. The overall and event free survival rates depend upon many prognostic factors. PURPOSE: To investigate treatment outcome for newly diagnosed MB patients treated at the Children's Cancer Hospital Egypt 57357 (CCHE) and to determine the working prognostic factors. PATIENTS AND METHODS: This study included all patients; treated at the CCHE; with histologically confirmed MB between Jan, 2008, and Jan, 2011. The Median age of the 73 (49 males (67.1%); 24 females (32.9%)) patients was 7 years (range 3-17). The median follow up period was 16 months (range 1-41). Risk stratification based upon initial Chang's stage, degree of surgical resection and histopathology. All patients had surgical resection o...

Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Cat. No.00CH37143), 2000