Animal type: mouse or rat Animal weight range: 8 – 1500g Diameter of mouse tail range: 3 – 6mm Diameter of rat tail range: 6 – 15mm

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Parameters provided include systolic blood pressure, mean blood pressure, calculated diastolic blood pressure and heart rate.

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Theodore W. Kurtz , Karen A. Griffin , Anil K. Bidani , Robin L. Davisson , and John E. Hall. Recommendations for Blood Pressure Measurement in Humans and Experimental Animals. Arteriosclerosis, Thrombosis, and Vascular Biology. 2005;25:e22–e33. Weblink

Steven E. Whitesall , Janet B. Hoff , Alan P. Vollmer , and Louis G. D'Alecy. Comparison of simultaneous measurement of mouse systolic arterial blood pressure by radiotelemetry and tail-cuff methods. Am J Physiol Heart Circ Physiol. 2004 Jun;286(6):H2408-15. Weblink

R D Buñag and J Butterfield. Tail-cuff blood pressure measurement without external preheating in awake rats. Hypertension. 1982;4:898–903. Weblink

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Kelly Gouveia, Jane L. Hurst. Reducing Mouse Anxiety during Handling: Effect of Experience with Handling Tunnels. PLoS One. June 2013; V8:e66401. Weblink

The monitor features an anodised “all round” heating unit to regulate animal temperature and improve accuracy/ reproducibility of assessments. The subjects are housed in one of a range of five sized net/ bag options designed to help provide a calm environment for measurement.

Conrado Johns , Irene Gavras , Diane E. Handy , Abrahao Salomao , and Haralambos Gavras. Models of Experimental Hypertension in Mice. Hypertension. 1996;28:1064–1069 Weblink

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Power source: Universal voltage, 100-230V, 80VA, 50 to 60Hz Dimensions: W x H x D mm, Weight: kg moorLAB-NIBP: 315 x 90 x 270, 2kg moorLAB-NIBP-HEAT: 315 x 90 x 270, 2kg Operating environment: Indoor, e.g. laboratory use Operating temperature: 15-30°C, 0 – 80% (non-condensing)

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Add additional “heat only” moorLAB-NIBP-HEAT modules to smooth workflow and increase measurement throughput by preparing animals in line ahead of measurement.

The system can operate as a single, standalone module using the clear, backlit LCD display, or together with moorLAB-NIBP-PC custom software for setup, display, analysis and data storage.

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The moorLAB-NIBP is a high performance, compact and automated non-invasive blood pressure measurement system for rats and mice

K. Ikeda , Y. Nara , Y. Yamori. Indirect systolic and mean blood pressure determination by a new tail cuff method in spontaneously hypertensive rats. Laboratory Animals (1991) 25, 26-29. Weblink

Moor Instruments, established in 1987, is a world leader in the design, manufacture and distribution of monitoring and imaging systems to assess blood flow and oxygen in the microvasculature. Whatever your needs, as a researcher, clinician or manufacturer, Moor will work harder for you.

Telephone: +44 (0)1297 35715 Fax: +44 (0)1297 35716 Email Enquiries: sales@moor.co.uk Email After Sales: service@moor.co.uk

Moor Instruments are committed to product development. We reserve the right to change the specifications below without notice.

Control channels: single for NIBP unit and dual for the HEAT unit Heating temperature range: 30 – 40 ºC (0.5 ºC increments) Typical time to reach heating temperature: <5 minutes (from 15 ºC ambient temperature)

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John N. Lorenz. A practical guide to evaluating cardiovascular, renal, and pulmonary function in mice. Am J Physiol Regul Integr Comp Physiol 282: R1565-1582, 2002. Weblink

John H. Krege , Jeffrey B. Hodgin , John R. Hagaman , and Oliver Smithies. A Noninvasive Computerized Tail-Cuff System for Measuring Blood Pressure in Mice. Hypertension. 1995;25:1111–1115. Weblink

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Heading to Neuroscience in Chicago? Join us at this year’s annual Society for Neuroscience meeting in Chicago! We’ll be at booth #1365 (right across the [...]

The moorLAB-NIBP is a new, compact, high performance, automated system, providing a complete and flexible solution for accurate and reliable blood pressure measurements in rats and mice.

Maximum cuff inflation: 350mmHg (5mmHg increments) Cuff pressure measurement range: 20 – 350mmHg Typical measurement cycle time: 20 seconds or less Heart rate measurement range: 100 – 1000BPM

R D Buñag. Validation in awake rats of a tail-cuff method for measuring systolic pressure. Journal of Applied PhysiologyVol. 34, No. 2. Weblink

Elena Wilde , Aisah A. Aubdool , Pratish Thakore , Lineu BaldisseraJr , Khadija M. Alawi , Julie Keeble , Manasi Nandi , and Susan D. Brain. Tail‐Cuff Technique and Its Influence on Central Blood Pressure in the Mouse. Journal of the American Heart Association. ;6:e005204. Weblink